Analysis of the mortality by eye cancer from 2010 to 2019 in Brazil / Análise da mortalidade no Brasil por câncer ocular de 2010 a 2019

ABSTRACT Objective: To assess the deaths caused by eye cancer from 2010 to 2019 in Brazil. Methods: Data were selected from SUS' Computer Department platform at the Ministry of Health, including death certificates, from 2010 to 2019, from all Brazilian states and the Federal District, filtering the codes C69.0 to C69.9 as the cause of death, according to the International Classification of Diseases, Tenth Revision. Results: There were 1,859 deaths from malignant neoplasm of eye and adnexa (C69), in Brazil, from 2010 to 2019, affecting 1,062 (57.1%) men. The site of neoplasm was unspecified (C69.9) in 719 cases, representing the most frequent etiology in the C69 group (38.67%). The malignant neoplasm of the orbit (C69.6) was the second most common cause of death (22.59%), followed by malignant neoplasm of retina (C69.2) (14.73%). Conclusion: The number of deaths due to malignant neoplasm of eye and adnexa slightly increased through the years of 2010 to 2019, in Brazil.

RESUMO Objetivo: Avaliar os óbitos causados por câncer ocular durante os anos de 2010 a 2019 no Brasil. Métodos: Os dados foram selecionados na plataforma do Departamento de Informática do SUS do Ministério da Saúde, incluindo declarações de óbito, durante os anos de 2010 a 2019, de todos os estados brasileiros e do Distrito Federal, filtrando os códigos C69.0 a C69.9 como causa básica de óbito, de acordo com a Classificação Internacional de Doenças e Problemas Relacionados à Saúde - 10ᵃ Revisão. Resultados: Houve 1.859 óbitos por neoplasia maligna de olho e anexos (C69), no Brasil, no período de 2010 a 2019, acometendo 1.062 (57,1%) homens. O sítio da neoplasia não foi especificado (C69.9) em 719 casos, representando a etiologia mais frequente no grupo C69 (38,67%). A neoplasia maligna da órbita (C69.6) foi a segunda causa mais comum de óbito (22,59%), seguida pela neoplasia maligna da retina (C69.2) (14,73%). Conclusão: O número de óbitos por neoplasia maligna de olho e anexos aumentou discretamente ao longo dos anos de 2010 a 2019, no Brasil.

Seroprevalence and factors associated with SARS-CoV-2 infection among education workers after the first wave: the first cross-sectional study in Brazil

ABSTRACT Background: The school community was heavily impacted by the Covid-19 pandemic, especially with the long time of school closures. This study aimed to analyze the seroprevalence of SARS-CoV-2 antibodies and possible factors associated with seropositivity for COVID-19 in teachers and other school staff, and to estimate the fraction of asymptomatic individuals by sex and age group. Methods: We conducted a serological survey of SARS-CoV-2 infections. An analytical cross-sectional study was conducted in Fortaleza, Brazil. Teachers and other staff members from pre-schools to universities of higher education to were investigated. Results: A total of 1,901 professionals participated in the study, of which 1,021 were staff and 880 were teachers. The seroprevalence of SARS-CoV-2 was 8.0% (152/1901). In the seropositive group, 48.3% were asymptomatic. There was a predominance of women (68.4%); and, 47.1% of the participants were between 31 and 45 years old. There was an increase in prevalence with increasing age. An inverse relationship was found for education level: more professionals with less education tested positive for COVID-19. The presence of an infected person living in the same household was significantly associated with positive results for COVID-19 among the professionals. Conclusions: This is the first study to report the seroprevalence of IgG against SARS-CoV-2 in Brazilian educational staff after the first wave of the disease. In this study, the seroprevalence was much lower than that in the general population. During school reopening, a small fraction of school workers showed serologically detectable signs of SARS-CoV-2 exposure.

Effects of the COVID-19 on the public interest in medical specialties in Brazil

SUMMARY OBJECTIVE: The aim of this study was to evaluate the effects of the COVID-19 pandemic and the social isolation on the interest rates of different medical specialties in Brazil. METHODS: The research was performed using the terms "Médico" (Doctor), "Infectologista" (Infectologist), "Cirurgião" (Surgeon), "Geriatra" (Geriatrician), "Otorrinolaringologista" (Otolaryngologist), and "Oftalmologista" (Ophthalmologist), related to several medical specialties, and "COVID-19," which represented the public interest for the disease, utilizing the Brazilian version of Google Trends, where the data were acquired. The time range of this analysis was from 29 September, 2019 to 20 September, 2020. The data were tabulated in Microsoft Excel, exported to the Statistical Package for the Social Sciences software, and correlated with searches for the term "COVID-19" using Pearson's correlation. 95% confidence interval was used for all analyses. RESULTS: "Geriatra" (72.26±16.42) and "Cirurgião" (72.15±12.53) remained with the higher means among the evaluated specialties. In terms of standard deviation, "Oftalmologista" (64.71±16.72) and "Infectologista" (22.03±16.60) presented the most significant changes. After utilizing the Pearson's analysis to identify the correlation between each medical specialty and the term "COVID-19," all the evaluated specialties presented significant statistical correlations. "Oftalmologista" (r= -0.607) was notoriously the most negatively affected, while "Infectologista" (r=0.504) was pointed to have the highest positive correlation with the term. CONCLUSIONS: Several changes in the interest rates of different medical specialties in Brazil were found during the time range of the COVID-19 pandemic.

Qualidade de vida em estudantes de odontologia na Pandemia de COVID-19: um estudo multicêntrico / Quality of life in dentistry students in the Pandemic of COVID-19: a multicentric study

O objetivo deste estudo foi avaliar a qualidade de vida (QV) de estudantes de Odontologia de Instituições de Ensino Superior (IES) do Estado do Ceará, Brasil, na pandemia de Coronavirus Disease 2019 (COVID-19). O método utilizado foi um estudo transversal, e a coleta de dados ocorreu em maio de 2020, online, por meio de questionários com variáveis sociodemográficas, as relacionadas ao curso e as comportamentais, além do World Health Organization Questionnaire for Quality of Life-bref (WHOQOL-bref). Foi realizada regressão logística multinomial. Participaram 864 estudantes. Variáveis como maior renda (p = 0,034), possuir religião (p = 0,010), possuir plano de saúde (p = 0,005), satisfação com a qualidade do sono (p < 0,001), ausência de insônia (p < 0,001) e praticar atividade física (p < 0,001) foram associadas à maior satisfação quanto à QV. A QV dos estudantes foi classificada insatisfatória, talvez impactada pela COVID-19. Variáveis que refletiram uma condição de vida mais favorável economicamente estiveram associadas à satisfação com a qualidade de vida desse público na pandemia.

This study aimed to assess the quality of life (QOL) of dental students in the 2019 Coronavirus Disease pandemic (COVID-19). A cross-sectional study was carried out with undergraduate students in Dentistry from Higher Education Institutions (HEIs) in the state of Ceará, Brazil. Data collection took place in May 2020, online, using questionnaires with sociodemographic, course-related and behavioral variables, in addition to the World Health Organization Questionnaire for Quality of Life-bref (WHOQOL-bref). Multinomial logistic regression was performed. 864 students participated in this study. Variables such as higher income (p = 0.034), having religion (p = 0.010), having health insurance (p = 0.005), satisfaction with sleep quality (p < 0.001), absence of insomnia (p < 0.001) and practicing physical activity always (p < 0.001) were associated with greater satisfaction regarding QOL. The QoL of dental students was classified in the dissatisfaction category, being perhaps impacted by the pandemic of COVID-19. Variables that reflected a more economically favorable living condition were associated with satisfaction with the quality of life of this public in the COVID-19 pandemic.

Oral health in the analysis of patients with hearing disabilities / Saúde bucal na análise de pacientes com deficiência auditiva

Objective: To assess the degree of knowledge of deaf and hard of hearing patients about oral health and relate it to clinical and demographic variables. Methods: The target population was schoolchildren from the 6th to the 9th grade of Elementary School and the 1st year of High School. Data collection took place through a structured questionnaire previously validated. The expressed as absolute and percentage frequencies it was analyzed using Fisher's exact test or Pearson's chi-square test (p <0.05). Results: Assessing the relationship between oral health and quality of life, to 53 students, 32.1% of students never reported pain in their teeth, mouth, or jaws, 55.8% never missed school due to problems with their teeth or dental treatments, 71, 2% never avoided smiling or laughing due to problems with teeth or dental treatments, 53.8% never avoided opening their mouths or talking due to problems with teeth or dental treatments. Conclusion: Professional and patient communication should be emphasized with the deaf and hard of hearing to intensify the importance of monitoring with the dental surgeon, carrying out activities to promote, prevent, cure, and rehabilitate oral health.

Objetivo: Avaliar o grau de conhecimento de pacientes portadores de deficiência auditiva sobre a saúde bucal, e relacionar com as variáveis clínicas e demográficas. Métodos: A população alvo foram escolares do 6º ao 9º ano do Ensino Fundamental e do 1º ano do Ensino Médio. A coleta de dados ocorreu de agosto a novembro de 2018, por meio de um questionário estruturado previamente validado. A análise dos dados foi realizada por meio do programa SPSS (Statistical Package of the Social Sciences) e expressos em forma de frequência absoluta e percentual e analisados pelo teste exato de Fisher ou qui-quadrado de Pearson (p<0,05). Resultados: Avaliando a relação da saúde bucal com a qualidade de vida de 53 alunos; 32,1% dos alunos nunca relataram dores nos dentes, na boca, ou nos maxilares, 55,8% nunca faltaram à escola devido problemas com os dentes ou tratamentos dentários, 71,2% nunca evitaram sorrir ou rir devido a problemas com os dentes ou tratamentos dentários, 53,8% nunca evitaram abrir a boca ou falar devido a problemas com os dentes ou tratamentos dentários. Conclusão: A comunicação profissional e paciente deve ser enfatizada com os portadores de deficientes auditivos, com o intuito de intensificar a importância do acompanhamento com o cirurgião dentista, realizando atividades de promoção, prevenção, cura e reabilitação à saúde bucal

Internal configuration of maxillary molars in a subpopulation of Brazil's Northeast region: A CBCT analysis

Abstract The present study aimed to evaluate the internal configuration of the maxillary molars of a population from the Northeast region of Brazil. Cone-beam computed tomography (CBCT) exams from 512 patients (1501 teeth) were evaluated regarding the anatomical configuration of the root canal system, according to Vertucci's classification. The images were obtained using a Prexion 3D scanner operating at 90 kVp and 4 mA. The voxel size was 0.125 mm and the cut thickness was 1 mm. The images were then analyzed in the Prexion 3D Viewer software. The data were analyzed statistically by Pearson's chi-square test, with 5% of significance. The first and second molars presented three roots in 99.14% and 87.27% of the cases, respectively. In relation to the number of canals, the first and second molars had a significantly higher frequency of three and four root canals respectively, presenting a higher prevalence of types I and II (p < 0.001). The second mesiobuccal canal (MB2) was observed in 48.21% and 22.72% of the first and second molars, respectively (p < 0.001). The identification of the MB2 canal was greater in young and adult patients (p < 0.001), presenting a higher prevalence in male patients (p < 0.001). The internal configuration of the MB root was influenced by gender and by age, presenting a higher prevalence of the MB2 in male patients younger than 50 years of age.

Criopreserved ovarian tissue transplantation and bone restoration metabolism in castrated rats / Transplante de tecido ovariano criopreservado e restauração do metabolismo ósseo em ratas castradas

ABSTRACT Objectives: to evaluate estradiol levels and autotransplantation heated ovarian tissue effects, after vitrification, on rats bone metabolism previously oophorectomized bilaterally. Methods: experimental study with 27 rats aged 11 to 12 weeks and weighing 200g to 300g, submitted to bilateral oophorectomy and ovarian tissue cryopreservation for subsequent reimplantation. Animals were divided into two groups, A and B, with 8 and 19 rats, respectively. Autotransplantation occurred in two periods according to castration time: after one week, in group A, and after one month in group B. Serum estradiol measurements and ovary and tibia histological analysis were performed before and after oophorectomy period (early or late) and one month after reimplantation. Results: in groups A and B, tibia median cortical thickness was 0.463±0.14mm (mean±SD) at the baseline, 0.360±0.14mm after oophorectomy and 0.445±0.17mm one month after reimplantation p<0.005). Trabecular means were 0.050±0.08mm (mean±SD) at baseline, 0.022±0.08mm after oophorectomy and 0.049±0.032mm one month after replantation (p<0.005). There was no statistical difference in estradiol variation between the two study groups (p=0.819). Conclusion: cryopreserved ovarian tissue transplantation restored bone parameters, and these results suggest that ovarian reimplantation in women may have the same beneficial effects on bone metabolism.

RESUMO Objetivos: avaliar os níveis de estradiol e os efeitos do autotransplante de tecido ovariano aquecido, após vitrificação, no metabolismo ósseo de ratas previamente ooforectomizadas bilateralmente. Métodos: trabalho experimental com 27 ratas com idades entre 11 e 12 semanas e pesando 200g a 300g, submetidas à ooforectomia bilateral e criopreservação de tecido ovariano para posterior reimplante. Os animais foram divididos em dois grupos, A e B, com oito e 19 ratas, respectivamente. O autotransplante ocorreu em dois períodos de acordo com o tempo de castração: após uma semana, no grupo A, e após um mês no grupo B. Mensurações de estradiol sérico e análise histológica de ovário e tíbia foram feitos antes e após o período de ooforectomia (precoce ou tardio) e um mês após o reimplante. Resultados: nos grupos A e B, as espessuras corticais médias da tíbia foram 0,463±0,14mm (média±DP) na linha de base, 0,360±0,14mm após ooforectomia e 0,445±0,17mm em um mês após o reimplante (p<0,005). As médias trabeculares foram 0,050±0,08mm (média±DP) na linha de base, 0,022±0,08mm após ooforectomia e 0,049±0,032mm em um mês após o reimplante (p<0,005). Não houve diferença estatística entre a variação do estradiol entre os dois grupos de estudo (p=0,819). Conclusão: o transplante de tecido ovariano criopreservado restabeleceu os parâmetros ósseos, e estes resultados sugerem que a reimplantação ovariana em mulheres pode apresentar os mesmos efeitos benéficos sobre o metabolismo ósseo.